Anaphylaxis is the most severe allergy reaction, that involves many different parts of human body systems including skin, airways, digestion system, and cardiovascular system. The most dangerous of anaphylaxis reaction is death!
Anaphylaxis reaction will appear when a patient has got a sensitization from certain allergen exposure. This exposure will wake up some reaction from patient’s entire body. In a simple way, your body has an immune system whose job is to produce antibody to fight any ‘invader’ who attacks immune system. The antibody is called IgE (immunoglobulin). IgE can attach itself onto mast cells and basophil (white blood cells).
After sensitization process, your immune system will keep a memory about the invader. Next time, when the same invader revisit your body, IgE will identifies it, and then releases chemical substances such as histamine and leucotriene from white blood cells, which can cause vein leakage in your entire body. The leakage will cause swollen to your body parts, and will drop down your blood pressure.
What you can actually see on a patient who has anaphylaxis is the following (in the actual order) :
Itchy on the entire body (skin, nose, throat and even eyes)
Redness on the skin
Urticaria (nettle-rash) in skin, and angio-oedema (swollen on face or tongue)
Hoarse voice, and difficult swallowing (caused by swollen throat)
Difficult breathing (caused by swollen and narrower airways)
Dropping blood pressure, and signs of fainting (quickening pulse)
Nausea, vomiting, diarrhea
Fainting, and death.